LONG NON-CODING RNA MALAT1 REGULATES OXALIPLATIN-RESISTANCE VIA MIR-324-3P/ADAM17 AXIS IN COLORECTAL CANCER CELLS

Long non-coding RNA MALAT1 regulates oxaliplatin-resistance via miR-324-3p/ADAM17 axis in colorectal cancer cells

Abstract Background Colorectal cancer (CRC) is one of the most general malignant tumors.Accumulating evidence implied that long non-coding RNA Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) participated in the tumorigenesis of CRC.However, the effect of MALAT1 in drug-resistance needed to be further illustrated.Methods Levels of MA

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Prediction of well-being and insight into work-life integration among physicians using machine learning approach.

There has been increasing interest in examining physician well-being and its predictive factors.However, few studies have revealed the characteristics associated with physician well-being and work-life integration using a machine learning approach.To investigate predictive factors of well-being and obtain insights into work-life integration, the su

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